A. Fibroid Tissue

Under this head we class the textural alteration occurring in atrophy of the gall-bladder after inflammation.

b. Anomalous osseous deposit - ossification, as elsewhere in mucous canals, takes place only as a consequence of previous textural alteration of another kind. Thus we find subserous osseous lamellae formed in the parietes of the gall-bladder, after it has been converted into a serofibrous capsule, in hydrops cystidis; or the fibroid tissue which is deve-loped in the parietes of the gall-bladder, as a consequence of inflammation and partial suppuration, may ossify.

c. Tubercular deposit in the biliary passages is of very rare occurrence.

d. Carcinoma of the biliary passages is chiefly met with as a complication of cancer of the liver, but also of the lumbar lymphatic glands, and of the stomach. It occurs either as an idiopathic nodulated deposit in the submucous tissue, in rare cases giving rise to annular stricture and degeneration of the entire bladder into a cancerous capsule, or as cancerous infiltration of the mucous membrane; or, as is more commonly the case, the biliary passages are attacked from without, cancerous growths in the vicinity perforate the parietes, and push their way into the cavity. The gall-bladder is most frequently attacked by hepatic cancer; the ductus choledochus by carcinoma of the lymphatic glands. Obturation of the passages and hemorrhage are common consequences of the affection.