Phlebitis from a wound complicated with the introduction of a deleterious substance. The wound, besides involving other structures, affects either a large vein or only capillaries. In the former case, the phlebitis following the wound is either the consequence of intense inflammation and of low suppuration in the soft parts, and in the wounded vein, - the general symptoms, if they are present, being not produced by the direct absorption of poisonous matter into the wound from without, but by the products of inflammation of the injured structures, and especially of the veins; or the case may be altogether different; the poisonous matter may penetrate into the vein when it is opened, and be taken up into the blood, - the general symptoms and the poisoning of the mass of the blood being here developed rapidly. According to the nature of the substance, there may or may not be a coagulation in the wounded vessel; when there is a coagulation, we have a further inflammation of the venous coats.

In a wound affecting the capillaries, the poisonous substance, either in a state of purity, or mixed with the products of consecutive inflammation and low suppuration, enters the vessels either directly through their open mouths, or by imbibition through their walls; the phenomena are then either general, or, in accordance with the quality of the substance, we have a coagulum in the vein, either near or at some distance from the wound, and inflammation extending from it.

Cancerous Phlebitis especially occurs in the uterine veins, from whence it extends into the internal spermatic, the hypogastric (internal iliac), and the femoral veins, in cases of cancer of the uterus. These veins are closed by a coagulum of cancer, especially of the encephaloid form, in various stages of metamorphosis. This coagulum finds its way into the venous blood by the absorption of the cancerous matter in various modes, either as blastema, or cancer-cells, or cancerous ichor. Hence this condition, when it actually occurs as phlebitis, is that form which is induced by a coagulation of blood and its metamorphosis.