3. Depositions, Metastases

Depositions, Metastases, are very frequent both in the subcutaneous and in the deeper layers of cellular tissue. The deposits are of purulent and ichorous nature, and are often very numerous and extensive. They sometimes result from a primary and spontaneous pyaemia, which has been occasioned by pus or sanies having been taken into the mass of the blood; and sometimes from a state of the circulating fluid, in which other processes, exanthemata, typhus, etc, have led to the generation of pus by the blood in a secondary manner.

4. Gangrene Of Cellular Tissue

Mortification is liable to take place in cellular tissue, not only as a consequence of inflammation, but under other conditions also, as a primary disease. Sometimes the tissue, at first congested, and dark red in color, changes into a blackish, very moist, shreddy, and friable pulp: at other times, after having formed a blackish-red, viscid pulp, it becomes a dry, tinder-like, crumbling eschar. Lastly, it sometimes degenerates into a white mass, shaded with dirty yellow or greenish, and is moist and extremely easily torn.

5. Adventitious Growths

The adipose and cellular tissue beneath the skin, as well as that which is collected in larger quantity in the internal regions of the body, is occasionally the seat of cysts. The contents of these growths are exceedingly various; sometimes being serous, sometimes resembling synovia, or gum (colloid), fatty, cholesteatomatous, or melanotic. Fibrous tumors occur in the same structures; calcareous concretions are very seldom met with, the only instances being that in which a fibrinous exudation in the fat vesicles becomes, as has been mentioned, converted into chalk, and that of cord-like growths, or smooth, or tuberous plates of bone, which occur in the fibroid callus of which the cicatrix of cellular tissue is composed. Tuberculous matter is deposited in young persons usually, and especially in children; the depositions occur in the subcutaneous tissue, and are more or less circumscribed: they soften and form a cheese-like or fatty pulp, and then exciting an inflammatory process in the integuments, which ends in ulceration, they make their way outwards. They are always associated with tuberculosis of the lymphatic glands, and frequently with the same disease in other parenchymatous organs.

Sarcomatous and cancerous growths are frequent in cellular tissue, and of the latter it is the genuine white medullary form, and the cancer me-lanodes that chiefly occur.

Among the entozoa, the filaria medinensis is met with in the subcutaneous cellular tissue.