This section is from the book "A Text-Book Of Materia Medica, Pharmacology And Therapeutics", by George F. Butler. Also available from Amazon: A text-book of materia medica, pharmacology and therapeutics.
Heroin - Diacetyl Morphine. - This is an acetic ester of morphine. It is a white crystalline powder, of faintly bitter taste, but practically insoluble in water, but rendered soluble with dilute acids. It is useful as a substitute for morphine as an antispasmodic in cough, and is particularly valuable in respiratory difficulties. It is less of a cerebral depressant. Its use can bring about a habit. Dose, 1/15-1/4 grain (0.005-0.1 Gm.).
Dionine - Monacetyl Morphine Hydrochloride. - This is much similar to the preceding, a single acetyl ester entering into the combination. It has much the same properties, but is deemed more poisonous. Severe poisoning has resulted. Dose, not to exceed 1/2 grain (0.012 Gm.).
Peronine. - This is an analogous compound - the benzyl ester of morphine. It is now rarely employed as a remedy. Dose, up to 1 grain (0.06 Gm.).
 
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